Dichloromethane → HCID 23682646, compound

HRID 1379799Notes

Reaction equation

HRID 1379799 reaction equation
[OH-].[Na+:2].[C:3]([C:5]1[CH:25]=[CH:24][C:8]([C:9]([N:11]=[C:12]2[N:16]([CH3:17])[C:15]([CH3:18])=[C:14]([C:19]([O:21]CC)=[O:20])[S:13]2)=[O:10])=[CH:7][CH:6]=1)#[N:4].C(Cl)Cl>CO>[C:3]([C:5]1[CH:25]=[CH:24][C:8]([C:9]([N:11]=[C:12]2[N:16]([CH3:17])[C:15]([CH3:18])=[C:14]([C:19]([O-:21])=[O:20])[S:13]2)=[O:10])=[CH:7][CH:6]=1)#[N:4].[Na+:2]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 14798Sodium HydroxideHCID 4249922HCID 4249922, compound

Product 1

HCID 23682646HCID 23682646, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

10% Aqueous sodium hydroxide solution (48 ml) was added to a mixture of ethyl 2-(4-cyanobenzoylimino)-3,4-dimethylthiazoline-5-carboxylate (9.88 g), methylene chloride (250 ml) and methanol (250 ml), followed by stirring at room temperature for 17 hours. The reaction mixture was concentrated under reduced pressure, and the precipitated crystals were collected by filtration to give sodium 2-(4-cyanobenzoylimino)-3,4-dimethylthiazoline-5-carboxylate (10.0 g).

Workup

  1. concentrationThe reaction mixture was concentrated under reduced pressure
  2. filtrationthe precipitated crystals were collected by filtration

Sources & evidence

ORD record
ord-10a66edc96fc466d824e4ad2fd402eae
Source dataset
uspto-grants-1997_09
Patent number
US05672712

Reaction notes

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