Ammonium thiocyanate → HCID 22908117, compound

HRID 1379800Notes

Reaction equation

HRID 1379800 reaction equation
[C:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7](Cl)=[O:8])=[CH:5][CH:4]=1)#[N:2].[S-:12][C:13]#[N:14].[NH4+]>CC(C)=O>[C:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([N:14]=[C:13]=[S:12])=[O:8])=[CH:5][CH:4]=1)#[N:2]

Participants

4

Reactant 2

HCID 15666Ammonium thiocyanateHCID 801724-Cyanobenzoyl chloride

Product 1

HCID 22908117HCID 22908117, compoundYield 98.5%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

4-Cyanobenzoyl chloride (10 g) was added in portions to a solution of ammonium thiocyanate (4.6 g) in acetone (100 ml) at room temperature, followed by heating under reflux for 10 minutes. The reaction mixture was ice-cooled, and after removal of the insoluble substance by filtration, the filtrate was evaporated under reduced pressure to give 4-cyanobenzoyl isothiocyanate (11.2 g).

Workup

  1. temperatureby heating
  2. temperatureunder reflux for 10 minutes
  3. temperaturecooled
  4. customafter removal of the insoluble substance
  5. filtrationby filtration
  6. customthe filtrate was evaporated under reduced pressure

Sources & evidence

ORD record
ord-b661a65567a24634aa726e08057dd14f
Source dataset
uspto-grants-1997_09
Patent number
US05672712

Reaction notes

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