Trifluoroacetate → HCID 67553374, compound

Participants

Reaction Steps

Prepared from 2-benzyloxycarbonylamino-2-methyl- N-[2,3,4,5-tetrahydro-2-oxo-1-[[2'-(aminomethyl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzazepin-3(R)-yl]propanamide, trifluoroacetate (Example 36, Step A) and glycine benzyl ester hydrochloride according to the procedure described in Example 46, Step A. 1H NMR (200 MHz, CD3OD): δ 1.38 (s, 6H), 1.82 (m, 1H), 2.18-2.60 (m, 3H), 3.86 (s, 2H), 4.13 (s, 2H), 4.32 (m, 1H), 4.84 (d, 15 Hz, 1H)i 4.99 (s, 2H), 5.11 (s, 2H), 5.30 (d, 15 Hz, 1H), 7.05-7.41 (m, 22H). FAB-MS: calculated for C46 H47N5O7 781; found 782 (M+H, 90%).

Provenance & Evidence