Hydrochloric Acid → HCID 22908200, compound

Participants

Reaction Steps

To a solid consisting of 70% of 1-(5-methylchroman-6-carbonyl)-2-t-butyl hydrazine and 30% of 1-(5-methylchroman-6-carbonyl)-1-t-butyl hydrazine was added 10 ml of dehydrated ethanol containing 10% of hydrochloric acid and then the resultant was heated under reflux for 30 minutes. After cooling with ice and water, the precipitated crystals were filtered to obtain 0.88 g of 1-(5-methylchroman-6-carbonyl)-2-t-butyl hydrazine hydrochloride with a melting point of 217° to 220° C. in a yield of 68%. The filtrate was concentrated to obtain 0.25 g of ethyl methylchromanate with a melting point of 79° to 80° C. in a yield of 29%.

Provenance & Evidence