3-(4-fluorophenyl)-1H-pyrazol-5-amine → 2-Chloro-N-(4-{[5-(4-fluoro-phenyl)-1H-pyrazol-3-ylamino]-methyl}-3-methyl-cyclohexyl)-5-trifluoromethyl-benzamide

HRID 138002Notes

Reaction equation

HRID 138002 reaction equation
[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][CH:7]2[CH2:8][CH:9]([CH3:18])[CH:10]([C:13]([O:14][CH2:15][CH3:16])=[O:17])[CH2:11][CH2:12]2)[cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]1.[F:27][c:28]1[cH:29][cH:30][c:31](-[c:34]2[cH:35][c:36]([NH2:39])[n:37][nH:38]2)[cH:32][cH:33]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][CH:7]2[CH2:8][CH:9]([CH3:18])[CH:10]([CH2:13][NH:39][c:36]3[cH:35][c:34](-[c:31]4[cH:30][cH:29][c:28]([F:27])[cH:33][cH:32]4)[nH:38][n:37]3)[CH2:11][CH2:12]2)[cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]1

Participants

3

Reactant 2

HCID 27591383-(4-fluorophenyl)-1H-pyrazol-5-amineHCID 57465893Ethyl 4-(2-chloro-5-(trifluoromethyl)benzamido)-2-methylcyclohexane carboxylate

Product 1

HCID 574658962-Chloro-N-(4-{[5-(4-fluoro-phenyl)-1H-pyrazol-3-ylamino]-methyl}-3-methyl-cyclohexyl)-5-trifluoromethyl-benzamide

Sources & evidence

ORD record
ord-5b0145209fb24e28a7563c3f220be095
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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