Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 54533151 | HCID 54533151 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 7-Hydroxyindole | HCID 2737651 | — |
Reaction Steps
Reaction of 2-nitro-3-benzyloxyphenylpyruvic acid (2 g.) with 10% palladium on carbon (2 g.) in acetic acid under hydrogen atmosphere is complete in 30 minutes. The mixture is filtered and the solvent is removed in vacuo. The remaining material is dissolved in glycerol and heated at 220° C. for 20 minutes. The desired product is obtained by sublimation under high vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04579865 |
|---|
| Source dataset | uspto-grants-1986_04 |
|---|
| ORD ID | ord-d65cb3b54b3f49c6afd7d870b060d9fa |
|---|
| Source note | uspto-grants-1986_04 |
|---|
