HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Isocyanato-4-methoxybenzene → Carbamic acid,(4-methoxyphenyl)-,1h-indol-7-yl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Isocyanato-4-methoxybenzene | HCID 79443 | — |
| Reactant | 7-Hydroxyindole | HCID 2737651 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | Carbamic acid,(4-methoxyphenyl)-,1h-indol-7-yl ester | HCID 20242122 | — |
Reaction Steps
To a solution of 7-hydroxyindole (0.7 g.) in ethyl ether (25 ml) and triethylamine (1 ml) is added 0.8 g. 4-methoxyphenyl isocyanate (Aldrich 23860-0). The reaction is stirred for 3 days at room temperature. The solvent is removed in vacuo and the remaining oil is purified by HPLC on silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04579865 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-0d3d79ab1fce4551a70c6636a84fdf01 |
| Source note | uspto-grants-1986_04 |