HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 13606706, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,3-Dichloro-2-isocyanatobenzene | HCID 604537 | — |
| Reactant | 1-(3-Aminopropyl)-4-(4-chlorobenzyl)piperazine trihydrochloride | HCID 20205739 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 13606706 | HCID 13606706 | 104% |
Reaction Steps
The procedure described in Example 29 was followed, using 2,6-dichlorophenyl isocyanate (1.88 g; 10 mmole), 1-(3-aminopropyl)-4-(4-chlorobenzyl)piperazine trihydrochloride (3.77 g; 10 mmole), methylene chloride (50 ml) and triethylamine (4.3 ml; 31 mmole). Recrystallization from methanol provided the title compound (2.75 g; 52% yield) as colorless crystals, m.p. 246°-248° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04579947 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-199f6b78581c475398a81a8b1c73565c |
| Source note | uspto-grants-1986_04 |