Chlorosulfonyl isocyanate → HCID 23325987, compound

HRID 1380217Notes

Reaction equation

HRID 1380217 reaction equation
Cl[S:2]([N:5]=[C:6]=[O:7])(=[O:4])=[O:3].[CH3:8][N:9]([NH:11][S:12]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[OH:21])(=[O:14])=[O:13])[CH3:10]>>[CH3:10][N:9]([NH:11][S:12]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[O:21][S:2]([N:5]=[C:6]=[O:7])(=[O:4])=[O:3])(=[O:14])=[O:13])[CH3:8]

Participants

3

Reactant 2

HCID 70918Chlorosulfonyl isocyanateHCID 23325986HCID 23325986, compound

Product 1

HCID 23325987HCID 23325987, compound

Procedure

To 5.2 ml (0.06 mole) chlorosulfonyl isocyanate in 75 ml dry xylenes was added 10.1 g (0.05 mole) of 2-(dimethylaminosulfamoyl)phenol in 15 ml xylenes, keeping the reaction temperature <5° C. This mixture was then heated to reflux temperature for 1 hour. The reaction solution was then cooled and the solvent evaporated to give an oil. The infrared spectrum showed NCO absorption at 2270 cm-1.

Workup

  1. customthe reaction temperature <5° C
  2. temperatureThis mixture was then heated
  3. temperatureto reflux temperature for 1 hour
  4. temperatureThe reaction solution was then cooled
  5. customthe solvent evaporated
  6. customto give an oil
  7. customNCO absorption at 2270 cm-1

Sources & evidence

ORD record
ord-70bbe8f6f42f4dadb775f7d764d6b3fe
Source dataset
uspto-grants-1986_04
Patent number
US04581059

Reaction notes

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