2,4-Dimethyl-3-pyridinecarboxylic acid → 2,4-Dimethyl-N-(3-{4-[2-(4-trifluoromethoxy-phenyl)-benzo[1,3]dioxol-2-yl]-piperidin-1-yl}-butyl)-nicotinamide
Reaction equation
[CH3:32][c:33]1[c:34]([C:35](=[O:36])[OH:37])[c:38]([CH3:42])[cH:39][cH:40][n:41]1.[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([C:10]2([CH:19]3[CH2:20][CH2:21][N:22]([CH:25]([CH2:26][CH2:27][NH2:28])[CH3:29])[CH2:23][CH2:24]3)[O:11][c:12]3[c:13]([cH:15][cH:16][cH:17][cH:18]3)[O:14]2)[cH:8][cH:9]1)([F:30])[F:31]>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([C:10]2([CH:19]3[CH2:20][CH2:21][N:22]([CH:25]([CH2:26][CH2:27][NH:28][C:35]([c:34]4[c:33]([CH3:32])[n:41][cH:40][cH:39][c:38]4[CH3:42])=[O:36])[CH3:29])[CH2:23][CH2:24]3)[O:11][c:12]3[c:13]([cH:15][cH:16][cH:17][cH:18]3)[O:14]2)[cH:8][cH:9]1)([F:30])[F:31]Participants
3
Sources & evidence
- ORD record
- ord-8996e64f6f294ffa98f8e887f02adc90
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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