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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 138038Generated: October 25, 2026

Hydrochloric Acid → Methyl 5-(difluoromethoxy)picolinate

https://huagongshe.com/reaction/138038

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
ReactantAcetonitrileHCID 6342—
ReactantCarbonate IonHCID 19660—
Reactant2-Chloro-2,2-difluoroacetophenoneHCID 238296—
ReactantMethyl 5-hydroxypyridine-2-carboxylateHCID 4715126—
ProductMethyl 5-(difluoromethoxy)picolinateHCID 57827732—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-dcc9bcbe11b24821a7d453767b78e575
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)