Potassium Carbonate → HCID 23325147, compound

Participants

Reaction Steps

A mixture of 1.99 g of 2,6-dichloroquinoxaline, 2.83 g of methyl 2-[[2-(4-hydroxyphenoxy)propionyl]oxy]ethylcarbamate, 1.4 g of potassium carbonate and 20 ml of N,N-dimethylformamide is stirred at room temperature overnight. For the working-up, the mixture is poured on to ice-water and extracted with ethyl acetate. The extracts are washed with water and sodium chloride solution, dried over sodium sulphate and evaporated. By chromatography on silica gel with hexane/ethyl acetate (2:1) there is obtained pure methyl 2-[[2-[p-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propionyl]oxy]ethylcarbamate; m.p. 103°-104.5° C.

Provenance & Evidence