HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(p-Methoxyphenyl)-2-propanone → 4-Dimethylamino-3-(4-methoxyphenyl)-3-buten-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(p-Methoxyphenyl)-2-propanone | HCID 31231 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | 4-Dimethylamino-3-(4-methoxyphenyl)-3-buten-2-one | HCID 53990102 | — |
Reaction Steps
35 g of 3-(4-methoxyphenyl)-2-propanone and 70 ml of dimethylformamide dimethyl acetal are heated at 70° C. for 3 hours. The reaction mixture is then evaporated to dryness in vacuo, and the residue is induced to crystallise with petroleum ether and the crystals are filtered off with suction. 43 g of 4-dimethylamino-3-(4-methoxyphenyl)-3-buten-2-one are obtained. Melting point 51° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04582834 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-d23d5eee193847b28a610448a6f07df4 |
| Source note | uspto-grants-1986_04 |