Ammonia → HCID 13580514, compound

HRID 1380511Notes

Reaction equation

HRID 1380511 reaction equation
CO[C:3](=[O:15])[CH2:4][N:5]1[CH2:9][CH:8]2[CH2:10][CH2:11][C:12](=[O:13])[N:7]2[C:6]1=[O:14].[NH3:16]>CO>[O:14]=[C:6]1[N:7]2[C:12](=[O:13])[CH2:11][CH2:10][CH:8]2[CH2:9][N:5]1[CH2:4][C:3]([NH2:16])=[O:15]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 54120427HCID 54120427, compound

Product 1

HCID 13580514HCID 13580514, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of tetrahydro-3,5-dioxo-1H-pyrrolo-[1,2-c]imidazole-2(3H)-acetic acid methyl ester (1.0 g, 0.004 mol) in methanol, 150 ml, is saturated with anhydrous ammonia. The mixture is allowed to stand 24 hours at room temperature. The solution is concentrated at reduced pressure to yield tetrahydro-3,5-dioxo-1H-pyrrolo[1,2-c]imidazole-2(3H)-acetic acid amide.

Workup

  1. concentrationThe solution is concentrated at reduced pressure

Sources & evidence

ORD record
ord-00679f2030fc4aed8e7b03621e85e513
Source dataset
uspto-grants-1986_04
Patent number
US04582838

Reaction notes

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