反应详情

Stir under reflux for 3 hours a mixture of 70 g (0.5 mole) of o-methoxythiophenol, 120.5 g (0.486 mole) of o-iodobenzoic acid 81.7 g (1.46 mole) of potassium hydroxide, 85 g (1.34 mole) of copper powder and 800 ml of water. Filter the reaction mixture hot and again filter the filtrate through celite. Acidify the filtrate with concentrated hydrochloric acid. Separate the precipitate, wash well with water and dry in vacuo at 70° C. to obtain the title product. (m.p. 198°-200° C.).

1. temperatureunder reflux for 3 hours
2. filtrationFilter the reaction mixture hot
3. filtrationagain filter the filtrate through celite
4. customSeparate the precipitate
5. washwash well with water
6. customdry in vacuo at 70° C.