Acrylic Acid → N-(3-(Dimethylamino)-2,2-dimethylpropyl)acrylamide

HRID 1380702Notes

Reaction equation

HRID 1380702 reaction equation
[CH3:1][N:2]([CH3:9])[CH2:3][C:4]([CH3:8])([CH3:7])[CH2:5][NH2:6].[C:10](O)(=[O:13])[CH:11]=[CH2:12]>C([O-])(=O)C.[Cu+2].C([O-])(=O)C.P(=O)(O)(O)O>[CH3:1][N:2]([CH3:9])[CH2:3][C:4]([CH3:8])([CH3:7])[CH2:5][NH:6][C:10](=[O:13])[CH:11]=[CH2:12]

Participants

5

Reactant 2

HCID 6581Acrylic AcidHCID 104477N,N,2,2-Tetramethylpropane-1,3-diamine

Product 1

HCID 88388N-(3-(Dimethylamino)-2,2-dimethylpropyl)acrylamideYield 71%

Reagents, catalysts & solvents 2

HCID 1004Phosphoric AcidCatalystHCID 8895Cupric acetateCatalyst

Procedure

Proceeding as in Example 1, 130 g 3-dimethylamino-2,2-dimethylpropylamine; 72 g acrylic acid; 3 g copper acetate; and 2 g 85% phosphoric acid were mixed. 130.5 g (71%) N-(3-dimethylamino-2,2-dimethylpropyl)acrylamide was isolated.

Sources & evidence

ORD record
ord-bb55b3dc2c684f2ea4db493f51671153
Source dataset
uspto-grants-1986_04
Patent number
US04582933

Reaction notes

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