Diethyl Ether → HCID 23325911, compound

Participants

Reaction Conditions

Reaction Steps

10,5 g (1,5 mole) lithium (finelly divided) and 76 g (0,5 mole) dimethylbicyclo[3.2.1]octane-8-one (4) were added to 800 ml ether (absolute). Into this mixture a solution of 92,3 g (9,75 mole) isopropylbromide in 300 ml absolute ether was dropwise added at -10° C. within 4 h. After 1 h of stirring at 40° C. the mixture was hydrolysed and processed for isolation in usual manner. By distillation over a turning band column 46 g (47%) of 10 having a boiling point (1 mm) of 76° C. resulted from the raw product. IR: 3500/3600 cm-1 (O--H).--NMR (CCl4): δ=0,91, s (1-, 5-CH3), 1,15, d, J=7 Hz (CH3 --CH--CH3), 1,55 ppm, br. s (6-, 7-CH2).C13H24O (M=196,32)

Provenance & Evidence