Chlorine → Benzene, 2-chloro-1-fluoro-4-(trifluoromethyl)-
Reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+]([O-])=O.[Cl:15]Cl>>[Cl:15][C:3]1[CH:4]=[C:5]([C:8]([F:11])([F:10])[F:9])[CH:6]=[CH:7][C:2]=1[F:1]Participants
3
Conditions
- Temperature
- 320 °C
Procedure
In a continuous process, about 8 parts per hour of 4-fluoro-3-nitrobenzotrifluoride vapors and about 15 parts per hour of chlorine gas were passed simultaneously through a vapor phase reactor maintained at a temperature of about 320° C. and the reaction product vapors were condensed and collected. The process was continued until about 40 parts of 4-fluoro-3-nitrobenzotrifluoride had been passed through the reactor, yielding about 36.3 parts of 3-chloro-4-fluorobenzotrifluoride product. The structure of the product was confirmed by spectral analysis.
Workup
- customcondensed
- customcollected
Sources & evidence
- ORD record
- ord-01e4c1e4164f452aa0b4225820afefe9
- Source dataset
- uspto-grants-1986_04
- Patent number
- US04582948
Reaction notes
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