HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,5-Diaminopyrimidine → 2-(2'-Methoxy-4'-chlorosulfonyl-phenyl)-purine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,5-Diaminopyrimidine | HCID 83703 | — |
| Reactant | 4-(Chlorosulfonyl)-2-methoxybenzoic acid | HCID 20184580 | — |
| Product | 2-(2'-Methoxy-4'-chlorosulfonyl-phenyl)-purine hydrochloride | HCID 20184529 | — |
Reaction Steps
Prepared analogously to Example C from 2.5 gm of 2-methoxy-4-chlorosulfonyl benzoic acid and 2.4 gm of 4,5-diamino-pyrimidine (crystalline product obtained from dihydorchloride and 1 mol of common salt) by refluxing for eight hours. The solid crude product was processed further without any purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04582837 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-6d842c7706d44ef9bc1746be111d8ca0 |
| Source note | uspto-grants-1986_04 |