Methanesulfonyl chloride → 5-Cyano-2-(2'-methoxy-4'-methanesulfonyloxy-phenyl)-benzimidazole

HRID 1380733Notes

Reaction equation

[C:1]([C:3]1[CH:20]=[CH:19][C:6]2[N:7]=[C:8]([C:10]3[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][C:11]=3[O:17][CH3:18])[NH:9][C:5]=2[CH:4]=1)#[N:2].[CH3:21][S:22](Cl)(=[O:24])=[O:23]>>[C:1]([C:3]1[CH:20]=[CH:19][C:6]2[N:7]=[C:8]([C:10]3[CH:15]=[CH:14][C:13]([O:16][S:22]([CH3:21])(=[O:24])=[O:23])=[CH:12][C:11]=3[O:17][CH3:18])[NH:9][C:5]=2[CH:4]=1)#[N:2]

Participants

Reactant 2

HCID 31297Methanesulfonyl chloride

HCID 13596041389469-43-2

Product 1

HCID 201845285-Cyano-2-(2'-methoxy-4'-methanesulfonyloxy-phenyl)-benzimidazole

Procedure

Prepared analogously to Example 1 from 5-cyano-2-(2'-methoxy-4'-hydroxy-phenyl)-benzimidazole and methanesulfonic acid chloride.

Sources & evidence

ORD record: ord-4803c6d913bf45c293c9cae588156a02
Source dataset: uspto-grants-1986_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04582837

Reaction notes

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