HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 8-(2'-Methoxy-4'-dimethylaminosulfonyl-phenyl)-purine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 4,5-Diaminopyrimidine | HCID 83703 | — |
| Reactant | 4-(Chlorosulfonyl)-2-methoxybenzoic acid | HCID 20184580 | — |
| Product | 8-(2'-Methoxy-4'-dimethylaminosulfonyl-phenyl)-purine hydrochloride | HCID 20184581 | — |
Reaction Steps
Prepared analogously to Example 51 from 2-methoxy-4-chlorosulfonyl-benzoic acid, aqueous dimethylamine solution, and 4,5-diamino-pyrimidine. The hydrochloride was recrystallized from ethanol/water (4:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04582837 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-124cdc4160634884ae47e8861d091964 |
| Source note | uspto-grants-1986_04 |