反应详情

A boiling suspension of lithium aluminum hydride (0.8 g) in absolute dioxan (100 ml) is mixed with 7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one (2.2 g, 0.01 mol) and then refluxed for 3 hours. While cooling with iced water, 10% ammonium chloride solution is added and the precipitate formed is suction filtered. The filtrate is concentrated (to about 20 ml) in vacuo, the white precipitate obtained is suction filtered and washed with a little dioxan. Yield: 0.9 g. Mp: 162°-163° C.

1. temperaturerefluxed for 3 hours
2. additionis added
3. customthe precipitate formed
4. filtrationfiltered
5. concentrationThe filtrate is concentrated (to about 20 ml) in vacuo
6. customthe white precipitate obtained
7. filtrationfiltered
8. washwashed with a little dioxan