HRID1380874

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID30658

5,6-Dimethoxy-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine

C13H19NO2

HCID270941

(4,5-Dimethoxy-2-nitrophenyl)acetic acid

C10H11NO6

HCID15045279

未命名化合物

PRODUCTS

生成物

结构：COc1cc2c(cc1OC)CC(N(C)CCCNC(=O)Cc1cc(OC)c(OC)cc1[N+](=O)[O-])CC2

HCID23324589

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

The title compound of this paragraph is prepared from 4,5-dimethoxy-2-nitrophenylacetic acid (5.25 g, 0.0217 mol) and of 1-amino-3-[N-methyl-N-(6,7-dimethoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane (6.04 g, 0.0218 mol) analogously to Example R(c). Yield: 8.6 g. Rf value: 0.8 (alumina, eluant: 95 parts by volume of methylene chloride+5 parts by volume of ethanol).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-04e3ede4f1144ba4a8ffc962ce41bf4a
来源数据集: uspto-grants-1986_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04584293
来源说明: uspto-grants-1986_04

反应 SMILES

[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][C:6]([CH2:11][C:12]([OH:14])=O)=[C:5]([N+:15]([O-:17])=[O:16])[CH:4]=1.[NH2:18][CH2:19][CH2:20][CH2:21][N:22]([CH3:37])[CH:23]1[CH2:32][CH2:31][C:30]2[C:25](=[CH:26][C:27]([O:35][CH3:36])=[C:28]([O:33][CH3:34])[CH:29]=2)[CH2:24]1.COC1C(OC)=CC=C2C=1CCC(NC)C2>C(O)C>[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][C:6]([CH2:11][C:12]([NH:18][CH2:19][CH2:20][CH2:21][N:22]([CH3:37])[CH:23]2[CH2:32][CH2:31][C:30]3[C:25](=[CH:26][C:27]([O:35][CH3:36])=[C:28]([O:33][CH3:34])[CH:29]=3)[CH2:24]2)=[O:14])=[C:5]([N+:15]([O-:17])=[O:16])[CH:4]=1