5,6-Dimethoxy-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine → 1-[2-(2-Amino-4,5-dimethoxy-phenyl)-ethylamino]-3-[N-methyl-N-(6,7-dimethoxy-1,2,3,4,-tetrahydronaphth-2-yl)-amino]-propane

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Reaction Steps

The title compound of this paragraph is prepared from 1-[2-(2-amino-4,5-dimethoxyphenyl)-1-oxo-ethylamino]-3-[N-methyl-N-(6,7-dimethoxy-1,2,3,4,-tetrahydronaphth-2-yl)-amino]-propane (7.8 g, 0.0165 mol) analogously to Example R(e). Yield: 2.7 g Rf value: 0.2 (alumina, eluant: 95 parts by volume of methylene chloride+5 parts by volume of ethanol).

Provenance & Evidence