HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4,5-Dimethoxy-2-nitro-phenyl)-acetic acid → 1-[2-(4,5-Dimethoxy-2-nitro-phenyl)-1-oxo-ethylamino]-3-[N-methyl-N-(7-methoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4,5-Dimethoxy-2-nitro-phenyl)-acetic acid | HCID 270941 | — |
| Reactant | 1-Amino-3-[N-methyl-N-(7-methoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane | HCID 23324588 | — |
| Product | 1-[2-(4,5-Dimethoxy-2-nitro-phenyl)-1-oxo-ethylamino]-3-[N-methyl-N-(7-methoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane | HCID 53757660 | — |
Reaction Steps
The title compound here is prepared from 4,5-dimethoxy-2-nitrophenylacetic acid (5.25 g, 0.0217 mol) and 1-amino-3-[N-methyl-N-(7-methoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane (5.4 g, 0.0217 mol) analogously to Example R(c). Yield: 8.2 g Mp: 116°-118° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04584293 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-8e76368f0fee4a5bab9aa82868fca77a |
| Source note | uspto-grants-1986_04 |