3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one → HCID 23324569, compound

HRID 1380897Notes

Reaction equation

HRID 1380897 reaction equation
[CH3:1][O:2][C:3]1[C:18]([O:19][CH3:20])=[CH:17][C:6]2[CH2:7][C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14]Cl)[CH2:10][CH2:11][C:5]=2[CH:4]=1.[CH2:21]([NH:24][CH:25]1[CH2:34][CH2:33][C:32]2[C:27](=[CH:28][C:29]([O:37][CH3:38])=[C:30]([O:35][CH3:36])[CH:31]=2)[CH2:26]1)[CH:22]=[CH2:23]>>[CH3:1][O:2][C:3]1[C:18]([O:19][CH3:20])=[CH:17][C:6]2[CH2:7][C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14][N:24]([CH2:21][CH:22]=[CH2:23])[CH:25]3[CH2:34][CH2:33][C:32]4[C:27](=[CH:28][C:29]([O:37][CH3:38])=[C:30]([O:35][CH3:36])[CH:31]=4)[CH2:26]3)[CH2:10][CH2:11][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 130925103-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-oneHCID 23324578HCID 23324578, compound

Product 1

HCID 23324569HCID 23324569, compound

Procedure

The title compound is prepared from 1-[7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-chloropropane and 2-allylamino-6,7-dimethoxy-1,2,3,4-tetrahydronaphthalene analogously to Example 1. Mp: 226°-228° C.

Sources & evidence

ORD record
ord-5ade34db7fd34f58a5d9d5164d0e62bf
Source dataset
uspto-grants-1986_04
Patent number
US04584293

Reaction notes

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