HCID 12381618, compound → 1-[7,8-Methylenedioxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-[N-methyl-N-(6,7-dimethoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane

HRID 1380899Notes

Reaction equation

HRID 1380899 reaction equation
[CH2:1]1[O:19][C:18]2[C:3](=[CH:4][C:5]3[CH2:11][CH2:10][N:9]([CH2:12][CH2:13][CH2:14]Cl)[C:8](=[O:16])[CH2:7][C:6]=3[CH:17]=2)[O:2]1.[CH3:20][O:21][C:22]1[CH:23]=[C:24]2[C:29](=[CH:30][C:31]=1[O:32][CH3:33])[CH2:28][CH:27]([NH:34][CH3:35])[CH2:26][CH2:25]2>>[CH2:1]1[O:19][C:18]2[C:3](=[CH:4][C:5]3[CH2:11][CH2:10][N:9]([CH2:12][CH2:13][CH2:14][N:34]([CH3:35])[CH:27]4[CH2:26][CH2:25][C:24]5[C:29](=[CH:30][C:31]([O:32][CH3:33])=[C:22]([O:21][CH3:20])[CH:23]=5)[CH2:28]4)[C:8](=[O:16])[CH2:7][C:6]=3[CH:17]=2)[O:2]1

Participants

3

Reactant 2

HCID 12381618HCID 12381618, compoundHCID 130925111-[7,8-methylenedioxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-chloropropane

Product 1

HCID 233245941-[7,8-Methylenedioxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-[N-methyl-N-(6,7-dimethoxy-1,2,3,4-tetrahydronaphth-2-yl)-amino]-propane

Procedure

The title compound is prepared from 1-[7,8-methylenedioxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-chloropropane and 6,7-dimethoxy-2-methylamino-1,2,3,4-tetrahydronaphthalene analogously to Example 1. Mp: 158° C. (decomp.).

Sources & evidence

ORD record
ord-84a69e58d4e4439f8bfa50c57a728172
Source dataset
uspto-grants-1986_04
Patent number
US04584293

Reaction notes

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