3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one → HCID 23324599, compound

HRID 1380900Notes

Reaction equation

HRID 1380900 reaction equation
[CH3:1][O:2][C:3]1[C:18]([O:19][CH3:20])=[CH:17][C:6]2[CH2:7][C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14]Cl)[CH2:10][CH2:11][C:5]=2[CH:4]=1.[Cl:21][C:22]1[CH:23]=[C:24]2[C:29](=[CH:30][C:31]=1[Cl:32])[CH2:28][CH:27]([NH:33][CH3:34])[CH2:26][CH2:25]2>>[CH3:1][O:2][C:3]1[C:18]([O:19][CH3:20])=[CH:17][C:6]2[CH2:7][C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14][N:33]([CH3:34])[CH:27]3[CH2:26][CH2:25][C:24]4[C:29](=[CH:30][C:31]([Cl:32])=[C:22]([Cl:21])[CH:23]=4)[CH2:28]3)[CH2:10][CH2:11][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 130925103-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-oneHCID 23324595HCID 23324595, compound

Product 1

HCID 23324599HCID 23324599, compound

Procedure

The title compound is prepared from 1-[7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-chloropropane and 6,7-dichloro-2-methylamino-1,2,3,4-tetrahydronaphthalene analogously to Example 1. Mp.: 130° C.

Sources & evidence

ORD record
ord-c1309c29e31d403daf9513624add4255
Source dataset
uspto-grants-1986_04
Patent number
US04584293

Reaction notes

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