3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one → HCID 23324590, compound

HRID 1380901Notes

Reaction equation

HRID 1380901 reaction equation
[CH3:1][O:2][C:3]1[C:18]([O:19][CH3:20])=[CH:17][C:6]2[CH2:7][C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14]Cl)[CH2:10][CH2:11][C:5]=2[CH:4]=1.[CH3:21][NH:22][CH:23]1[CH2:32][CH2:31][C:30]2[C:25](=[CH:26][C:27]3[O:35][CH2:34][O:33][C:28]=3[CH:29]=2)[CH2:24]1>>[CH3:1][O:2][C:3]1[C:18]([O:19][CH3:20])=[CH:17][C:6]2[CH2:7][C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14][N:22]([CH3:21])[CH:23]3[CH2:32][CH2:31][C:30]4[C:25](=[CH:26][C:27]5[O:35][CH2:34][O:33][C:28]=5[CH:29]=4)[CH2:24]3)[CH2:10][CH2:11][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 130925103-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-oneHCID 23324601N-Methyl-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxol-6-amine

Product 1

HCID 23324590HCID 23324590, compound

Procedure

The title compound is prepared from 1-[7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-chloropropane and 2-methylamino-6,7-methylenedioxy-1,2,3,4-tetra-hydronaphthalene analogously to Example 1. Mp: >148° C. (decomp.).

Sources & evidence

ORD record
ord-7fe4e25fd6e846d3b1d1cef8bd28444c
Source dataset
uspto-grants-1986_04
Patent number
US04584293

Reaction notes

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