HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 3-[4-(trifluoromethyl)phenyl]prop-2-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 3-[4-(Trifluoromethyl)phenyl]prop-2-enoic acid | HCID 74940 | — |
| Product | Ethyl 3-[4-(trifluoromethyl)phenyl]prop-2-enoate | HCID 53662772 | — |
Reaction Steps
A suspension of 300 g of 4-trifluoromethylcinnamic acid (J. Org. Chem. 43:980 (1978)) and 25 ml of concentrated sulfuric acid in 1.7 liters of ethanol is heated to reflux for 24 hours. The solution is concentrated, cooled, and filtered to give as a white solid, 4-trifluoromethylcinnamic acid ethyl ester, mp 40°-41° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04584313 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-770d4bc732f3484e93d74e60cade809d |
| Source note | uspto-grants-1986_04 |