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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1380955Generated: October 25, 2026

Hydrochloric Acid → HCID 86740742, compound

https://huagongshe.com/reaction/1380955

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPiperidineHCID 8082—
Reactant(2-Bromopropyl)benzeneHCID 102754—
Reactant4-[N-(4-fluorophenyl)methoxyacetamido]piperidineHCID 23324804—
SolventTolueneHCID 1140—
ProductHCID 86740742HCID 86740742—

Reaction Steps

Combining 1-phenyl-2-bromopropane with 4-[N-(4-fluorophenyl)methoxyacetamido]piperidine in the procedure similar to that of Example XII the base 1-(2-phenyl-1-propyl)-4-[N-4-fluorophenyl)methoxyacetamido]piperidine is formed. Dry HCl is added to a toluene solution of the base to obtain 1-(2-phenyl-1-propyl)-4-[N-(4-fluorophenyl)methoxyacetamido]piperidinium chloride, m.p. 250° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04584303
Source datasetuspto-grants-1986_04
ORD IDord-9d3b91c994cd4dee8a24936b76f97787
Source noteuspto-grants-1986_04