HCID 13051271, compound → HCID 57051172, compound

Participants

Reaction Steps

Benzene and saturated saline were added to the reaction mixture to extract the product into benzene. The separated benzene layer was further washed three times with saturated saline, dried over anhydrous sodium sulfate and concentrated to give crystals. The high-speed liquid chromatographic analysis of the crystals showed that 17β-ethynyl-17α-hydroxyandrosta-1,4-diene-3-one and 17-ethynylandrosta-1,4,16-trien-3-one were formed in yields of 63 mol % and 32 mol %, respectively.

Provenance & Evidence