HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-nitroanisole → 5-Fluoro-2-methoxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-nitroanisole | HCID 565656 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | HCID 178418361 | HCID 178418361 | — |
| Product | 5-Fluoro-2-methoxyaniline | HCID 223105 | — |
Reaction Steps
Reduction of 1-fluoro-3-nitro-4-methoxybenzene (34 g) in 400 ml of ethanol was carried out with 2 g of 10% palladium/carbon catalyst in hydrogen. The mixture was filtered, concentrated and used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04585773 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-91e5fb309b424494b3b074a55a800b95 |
| Source note | uspto-grants-1986_04 |