Ethyl isocyanate → HCID 13320288, compound

HRID 1381236Notes

Reaction equation

HRID 1381236 reaction equation
[CH2:1]([C:4]1[CH:18]=[CH:17][CH:16]=[CH:15][C:5]=1[O:6][C@@H:7]1[CH2:11][N:10]([CH2:12][CH3:13])[CH2:9][C@H:8]1[OH:14])[CH:2]=[CH2:3].[CH2:19]([N:21]=[C:22]=[O:23])[CH3:20]>C1C=CC=CC=1>[CH2:19]([NH:21][C:22]([O:14][C@H:8]1[C@H:7]([O:6][C:5]2[CH:15]=[CH:16][CH:17]=[CH:18][C:4]=2[CH2:1][CH:2]=[CH2:3])[CH2:11][N:10]([CH2:12][CH3:13])[CH2:9]1)=[O:23])[CH3:20]

Participants

4

Reactant 2

HCID 8022Ethyl isocyanateHCID 13320286HCID 13320286, compound

Product 1

HCID 13320288HCID 13320288, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

A mixture of 7.3 g. of trans 4-(2-allylphenoxy)-1-ethyl-3-pyrrolidinol and 2.5 g. of ethylisocyanate in 30 ml. of benzene was stirred for 48 hr. The benzene was replaced by petroleum ether and the solution chilled. The yield of precipitate melting at 53-6° C. was 78%.

Workup

  1. additionA mixture of 7.3 g
  2. temperaturethe solution chilled

Sources & evidence

ORD record
ord-269804e621344f35a0dd8e12b83e8316
Source dataset
uspto-grants-1986_04
Patent number
US04585785

Reaction notes

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