Potassium Hydroxide → HCID 12330021, compound

HRID 1381250Notes

Reaction equation

C([O:3][C:4]([C:6]1[CH:25]=[C:24]([C:26]([F:29])([F:28])[F:27])[CH:23]=[CH:22][C:7]=1[CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([CH2:16][C:17]([O:19]CC)=[O:18])=[CH:12][CH:11]=1)=[O:5])C.[OH-].[K+]>>[C:4]([C:6]1[CH:25]=[C:24]([C:26]([F:27])([F:29])[F:28])[CH:23]=[CH:22][C:7]=1[CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([CH2:16][C:17]([OH:19])=[O:18])=[CH:12][CH:11]=1)([OH:5])=[O:3]

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 21269157HCID 21269157, compound

Product 1

HCID 12330021HCID 12330021, compound

Procedure

Reaction of ethyl 4-(2-ethoxycarbonyl-4-trifluoromethylbenzyloxy)phenylacetate with potassium hydroxide as described in Example 1c provides 4-(2-carboxy-4-trifluoromethylbenzyloxy)phenylacetic acid, m.p. 185°-187°.

Sources & evidence

ORD record: ord-2b60ff086d4642d38f472b792bfd2e9d
Source dataset: uspto-grants-1986_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04585788

Reaction notes

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