Diethyl Ether → HCID 70451854, compound

Participants

Reaction Steps

A solution of 216 mg of p-[(R)-3-[bis-[(R)-β-hydroxyphenethyl]amino]butyl]benzamide in 2 ml of methanol was reacted with 58 mg of fumaric acid. After addition of 10 ml of ether to the solution, there were obtained 210 mg of p-[(R)-3-[bis[(R)-β-hydroxyphenethyl]amino]butyl]benzamide fumarate, which after crystallization from acetonitril, has a melting point of 92°-94°; [α]D20 =-81° (c=1,0 in methanol); ε234 =17400.

Provenance & Evidence