HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → Piperidine, 1-(2-phenoxyethyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Benzene, (2-bromoethoxy)- | HCID 68526 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Piperidine, 1-(2-phenoxyethyl)- | HCID 120169 | 96.4% |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A mixture of 20 g of 2-phenoxyethyl bromide thus obtained, 7.92 g of piperidine and 12.86 g of potassium carbonate was added into 100 ml of ethyl alcohol and stirred for 6 hours at 100° C. The mixture obtained was filtered and condensed under reduced pressure to give 18.4 g of 1-(2-phenoxyethyl)piperidine having a boiling point of 111° C. to 112° C. at 7 mmHg in a yield of 90%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04585869 |
| Source dataset | uspto-grants-1986_04 |
| ORD ID | ord-10d19b7a3e5c4d41bbedefa44b82a062 |
| Source note | uspto-grants-1986_04 |