Ammonium → 1-O-tert-butyl 3-O-methyl 4-aminopiperidine-1,3-dicarboxylate

HRID 138142Notes

Reaction equation

HRID 138142 reaction equation
[CH3:31][OH:32].[CH:27]([O-:28])=[O:29].[NH4+:30].[c:1]1([CH:2]([CH3:3])[NH:9][CH:10]2[CH:11]([C:23](=[O:24])[O:25][CH3:26])[CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:4][cH:5][cH:6][cH:7][cH:8]1>>[NH2:9][CH:10]1[CH:11]([C:23](=[O:24])[O:25][CH3:26])[CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]1

Participants

5

Reactant 4

HCID 223AmmoniumHCID 283FormateHCID 887MethanolHCID 68819527Methyl1-Boc-4-[[(R)-1-phenylethyl]amino]piperidine-3-carboxylate

Product 1

HCID 592166281-O-tert-butyl 3-O-methyl 4-aminopiperidine-1,3-dicarboxylate

Sources & evidence

ORD record
ord-88ed1d43a78e4cf4bd0d8f8f4a40dc50
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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