Potassium Carbonate → HCID 21276159, compound

Participants

Reaction Steps

A solution of 5-acetyloxycyclohepta[1,2-c]pyridine in hydrochloric acid (75 ml, ca. 5 N) was heated and stirred at its reflux temperature for 61/2 hrs. The resulting red-colored solution was stirred overnight, then neutralized with solid K2CO3 (pH=8) and the oily precipitate extracted with methylene chloride. The organic phase was separated, washed with brine, and dried (MgSO4). Filtration through celite gave a light yellow filtrate which on concentration gave a gummy brown solid. The solid was triturated with hexane and collected by filtration. The yield of light tan solid was 5.10 g (59%), m.p. 127°-129° C.

Provenance & Evidence