2-Methoxyaniline → HCID 178489585, compound

HRID 1381542Notes

Reaction equation

HRID 1381542 reaction equation
[C:1]1([CH3:16])[CH:6]=[CH:5][C:4]([S:7]([N:10]2[CH2:14][CH2:13][C:12]([NH2:15])=[N:11]2)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[CH3:17][O:18][C:19]1[C:20](N)=[CH:21][CH:22]=[CH:23][CH:24]=1>C(O)(=O)C>[CH3:17][O:18][C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:24]=1[NH:15][C:12]1[CH2:13][CH2:14][N:10]([S:7]([C:4]2[CH:3]=[CH:2][C:1]([CH3:16])=[CH:6][CH:5]=2)(=[O:9])=[O:8])[N:11]=1

Participants

4

Reactant 2

HCID 70002-MethoxyanilineHCID 434511ST50975259

Product 1

HCID 178489585HCID 178489585, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 4,5-dihydro-1-(4-toluenesulphonyl)-1H-pyrazol-3-amine (8.08 g) (Organic Synthesis 48,8, (1968)), o-anisidine (8.0 g) and glacial acetic acid (80 ml) was heated on a steam bath for 4 hours. The reaction mixture was cooled, filtered and washed with ether to give the sub-title product, 7.6 g, mp 176°-9°.

Workup

  1. temperaturewas heated on a steam bath for 4 hours
  2. temperatureThe reaction mixture was cooled
  3. filtrationfiltered
  4. washwashed with ether

Sources & evidence

ORD record
ord-6dd28f1764f549d5b2fabab91b7794f4
Source dataset
uspto-grants-1989_02
Patent number
US04803216

Reaction notes

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