HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Nitro-3-(2-nitropropyl)indole → 5-Amino-3-(2-nitropropyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Nitro-3-(2-nitropropyl)indole | HCID 14391138 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-Amino-3-(2-nitropropyl)indole | HCID 14391139 | 70% |
Reaction Steps
A solution of 1.5 g (0.006 mole) of 5-nitro-3-(2-nitropropyl)indole in 150 ml of EtOH treated with 100 mg of PtO2 was hydrogenated (Parr) for 15 minutes. The catalyst was filtered and solvent removed in vacuo to give a yellow product which solidified on standing. Recrystallization from EtOH afforded 0.9 g (70%) of desired product: m.p. 120°-121.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04803218 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-6ca167f6fdfa438f9d487e6cef21ca71 |
| Source note | uspto-grants-1989_02 |