4-Acetyl-3-hydroxy-2-propylbenzyl chloride → HCID 14053133, compound

HRID 1381580Notes

Reaction equation

HRID 1381580 reaction equation
[C:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8]Cl)=[C:6]([CH2:12][CH2:13][CH3:14])[C:5]=1[OH:15])(=[O:3])[CH3:2].[SH:16][C:17]1[S:21][C:20]([S:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])=[N:19][N:18]=1>>[C:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8][S:16][C:17]2[S:21][C:20]([S:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])=[N:19][N:18]=2)=[C:6]([CH2:12][CH2:13][CH3:14])[C:5]=1[OH:15])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 137810224-Acetyl-3-hydroxy-2-propylbenzyl chlorideHCID 178471458HCID 178471458, compound

Product 1

HCID 14053133HCID 14053133, compoundYield 92.4%

Procedure

Using as starting materials 0.30 g of 4-acetyl-3- hydroxy-2-propylbenzyl chloride and 0.46 g of ethyl 6-[(5- mercapto-1,3,4-thiadiazol-2-yl]thio]hexanoate, 0.59 g of oily ethyl 6-[[5-[(4-acetyl-3-hydroxy-2-propylbenzyl)thio]-1,3,4- thiadiazol-2-yl]thio]hexanate was obtained in a manner similar to Example 9.

Sources & evidence

ORD record
ord-9d4a9534f0cd4bc7be063ba9fb92808b
Source dataset
uspto-grants-1989_02
Patent number
US04803211

Reaction notes

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