HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → HCID 14405966, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Bromoacetic Acid | HCID 6227 | — |
| Reactant | 2-(4-Chlorophenyl)-1-(piperidin-1-yl)ethane-1-thione | HCID 13546141 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 14405966 | HCID 14405966 | 77.9% |
Reaction Steps
A mixture of 200 g of N-(4-chlorophenylthioacetyl)piperidine, 117.5 g of bromoacetic acid and 600 ml of benzene was stirred overnight, then diluted with anhydrous ether and stirred overnight. The solid was collected and dried in vacuo giving 241 g of 1-[1-[(carboxymethyl)thio]2-(4-chlorophenyl)ethylidene]piperidinium bromide, mp 118°-120° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04803280 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-932198875ccb4b5495afaaac2cc4bc4c |
| Source note | uspto-grants-1989_02 |