HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → N-(2-fluoro-5-chlorocarbonyl-4-chlorophenyl)-2,3-dimethylmaleic acid imide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,3-Dimethylmaleimide | HCID 28793 | — |
| Reactant | N-(2-fluoro-4-chloro-5-carboxyphenyl)-2,3-dimethylmaleic acid imide | HCID 17802070 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-(2-fluoro-5-chlorocarbonyl-4-chlorophenyl)-2,3-dimethylmaleic acid imide | HCID 17802075 | — |
Reaction Steps
A mixture of 6 g of N-(2-fluoro-5-carboxy-4-chlorophenyl)-2,3-dimethylmaleic acid imide, 0.5 ml of dimethylmaleinimide, 2 ml of thionyl chloride and 50 ml of toluene is heated under reflux for 4 hours. After cooling, the whole is concentrated by evaporation in vacuo. 6 g of N-(2-fluoro-5-chlorocarbonyl-4-chlorophenyl)-2,3-dimethylmaleic acid imide having a melting point of 123°-124° are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04804400 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-ebdde2bcd03c4da9a40bc19c0fa3ea26 |
| Source note | uspto-grants-1989_02 |