N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide → N-({1-[4-(5-Iodo-2-oxo-2H-pyridin-1-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide

HRID 138185Notes

Reaction equation

HRID 138185 reaction equation
[I:1][c:2]1[cH:3][cH:4][c:5](=[O:15])[n:6]([CH:8]2[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]2)[cH:7]1.[NH:16]1[CH2:17][CH:18]([NH:20][C:21](=[O:22])[CH2:23][NH:24][C:25]([c:26]2[cH:27][c:28]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:30][cH:31]2)=[O:36])[CH2:19]1>>[I:1][c:2]1[cH:3][cH:4][c:5](=[O:15])[n:6]([CH:8]2[CH2:9][CH2:10][CH:11]([N:16]3[CH2:17][CH:18]([NH:20][C:21](=[O:22])[CH2:23][NH:24][C:25]([c:26]4[cH:27][c:28]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:30][cH:31]4)=[O:36])[CH2:19]3)[CH2:12][CH2:13]2)[cH:7]1

Participants

3

Reactant 2

HCID 59361594N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamideHCID 667518565-iodo-1-(4-oxo-cyclohexyl)-1H-pyridin-2-one

Product 1

HCID 49764697N-({1-[4-(5-Iodo-2-oxo-2H-pyridin-1-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide

Sources & evidence

ORD record
ord-c29755ab660b44849e037aa8d5e9c2ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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