反应详情

In the manner described in Example 1, 1.8 grams (8.0 mmoles) of (chloromethyl)(4-ethoxyphenyl)dimethylsilane was reacted with 1.7 grams (8.0 mmoles) of 6-phenoxy-2-pyridine methanethiol giving 3.2 grams of a light orange oil. The product was purified on a Waters® Prep 500A liquid chromatograph (silica gel) eluting with 6 percent ethylacetate in hexane, to yield 2.7 grams of (4-ethoxyphenyl)dimethyl[(((6-phenoxy-2-pyridinyl)methyl)thio)methyl]silane as a clear oil. Analytical data for this product are shown in Table VI.

1. customThe product was purified on a Waters® Prep 500A liquid chromatograph (silica gel)
2. washeluting with 6 percent ethylacetate in hexane