Methanesulfonyl chloride → HCID 13559066, compound

Participants

Reaction Steps

11 g (0.1 mol) of methanesulphonyl chloride are added dropwise, with stirring at 0° C. to 14 g (0.074 mol) of 2-methyl-3-β-naphthylpropanol (crude) in 80 ml of absolute pyridine, the mixture is stirred for a further 16 hours at room temperature after the addition is complete, excess pyridine is removed by distillation in vacuo, the residue is taken up in water, extracted repeatedly with dichloromethane and dried over sodium sulphate, and the solvent is removed in vacuo. 13.6 g (66% of theory) of 1-methanesulphonyloxy-2-methyl-3-β-naphthyl-propane are obtained as an oil. (IR: ν=1345, 1180 cm-1). ##STR45##

Provenance & Evidence