Hydrochloric Acid → HCID 14371875, compound

Participants

Reaction Steps

To a solution of 8-benzyloxycarbonyl-2-benzyloxycarbonyloxy-2,8-diazaspiro[4,5]decane-1,3-dione (5.6 g) in dichloromethane (50 ml) was added N,N-dimethyl-1,3-propanediamine (1.9 ml), and the mixture was stirred overnight at room temperature, to which was then added 1N hydrochloric acid (50 ml). The organic layer was washed with water, dried over anhydrous magnesium sulfate. The solvent was then evaporated off. The residual solid was recrystallized from ethyl ether-n-hexane to obtain 3.8 g of a colorless solid, m.p. 131° to 132° C.

Provenance & Evidence