Bromonitromethane → HCID 14371879, compound

HRID 1381960Notes

Reaction equation

HRID 1381960 reaction equation
[CH2:1]([O:8][C:9]([N:11]1[CH2:23][CH2:22][C:14]2([C:18](=[O:19])[N:17]([OH:20])[C:16](=[O:21])[CH2:15]2)[CH2:13][CH2:12]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:25][N+:26]([O-:28])=[O:27]>>[CH2:1]([O:8][C:9]([N:11]1[CH2:23][CH2:22][C:14]2([C:18](=[O:19])[N:17]([O:20][CH2:25][N+:26]([O-:28])=[O:27])[C:16](=[O:21])[CH2:15]2)[CH2:13][CH2:12]1)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 68423BromonitromethaneHCID 14371875HCID 14371875, compound

Product 1

HCID 14371879HCID 14371879, compound

Procedure

Employing 8-benzyloxycarbonyl-2-hydroxy-2,8-diazaspiro[4,5]decane-1,3-dione (0.64 g) and bromonitromethane (140 μl), reaction was conducted in the same manner as in Example 40 to obtain 0.25 g of a colorless solid, m.p. 137° to 139° C.

Sources & evidence

ORD record
ord-22ef0409e52748bba05fe4d8428d8237
Source dataset
uspto-grants-1989_02
Patent number
US04804665

Reaction notes

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