HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → Hydrazine hydrate (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | Methyl 4-acetamido-2-methoxy-5-nitrobenzoate | HCID 77723 | — |
| Reactant | Sodium 2-methoxy-4-amino-5-nitrobenzoate | HCID 21275767 | — |
| Product | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Product | 4,5-Diamino-o-anisic acid | HCID 101017 | — |
Reaction Steps
In general, reaction of methyl 2-methoxy-4-acetylamino-5-nitrobenzoate with the base is preferably immediately followed by the in-situ reaction of the intermediate sodium-2-methoxy- 4-amino-5-nitrobenzoate (intermediate I) with hydrazine or its equivalent, preferably as hydrazine hydrate, to form 2-methoxy-4,5-diaminobenzoic acid (intermediate II). That product is preferably recovered and purified prior to further use.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04804765 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-c6ea9cca305d4b5792bf9487e008496f |
| Source note | uspto-grants-1989_02 |